What is metformin?
Metformin is an oral medication that lowers blood glucose (sugar) by influencing the body's sensitivity to insulin and is used for treating type 2 diabetes. Insulin is a hormone produced by the pancreas that controls glucose levels in blood by reducing the amount of glucose made by the liver and by increasing the removal of glucose from the blood by muscle and fat tissues. As a result, insulin causes blood glucose levels fall. Diabetes caused by a decrease in production of insulin that causes increased production of glucose by the liver, and reduced uptake (and effects) of insulin on fat and muscle tissues. Metformin acts by increasing the sensitivity of liver, muscle, fat, and other tissues to the uptake and effects of insulin. These actions lower the level of sugar in the blood.
Unlike glucose-lowering drugs of the sulfonylurea class, for example glyburide (Micronase, DiaBeta) or glipizide (Glucotrol), metformin does not increase the concentration of insulin in the blood and, therefore, does not cause excessively low blood glucose levels (hypoglycemia) when used alone. In scientific studies, metformin reduced the complications of diabetes such as heart disease, blindness, and kidney disease
What are the uses for metformin?
Metformin is used for treating type 2 diabetes in adults and children. It may be used alone or in combination with other diabetic medications.
Metformin also has been used to prevent the development of diabetes in people who are at risk.
Treatment of polycystic ovaries
Weight gain due to medications used for treating psychoses.
What are the side effects of metformin?
The most common side effects with metformin are
loss of appetite.