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1P-LSD also known as 1-Propionyl-d-lysergic acid diethylamide is a novel psychedelic substance of the lysergamide class that is a derivative and functional analog of LSD and a homolog of ALD-52. Buy 1P-LSD Blotters, Order Cheap 1P-LSD Discreetly.
1P-LSD is closely related to LSD and is reported to produce near-identical effects. Due to its novelty, little is known about the pharmacology of 1P-LSD, but it is thought to produce its effects by binding to serotonin receptors in the brain.
1cP-LSD has been sold online as a designer drug and research chemical since 2015, but the original synthesis date of 1P-LSD is unknown.
Unlike most research chemicals, 1P-LSD has no documented record in the research literature before its emergence on the online research chemical market in 2015.
It was marketed as a legal alternative to LSD alongside other novel lysergamides like ALD-52, ETH-LAD, and AL-LAD. In 2019, it became part of a group of molecules studied by the French laboratory Caulredaitens.
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Anecdotal reports from many users suggest that the subjective effects of 1P-LSD are so similar to that of LSD to be virtually indistinguishable from one another.
In comparison to other psychedelics such as psilocybin, LSA, and ayahuasca, 1P-LSD is significantly more stimulating and fast-paced regarding the specific style of its physical and cognitive effects.
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- Stimulation – 1P-LSD is usually regarded as very energetic and stimulating without being forced. For example, when taken in any environment it will usually encourage physical activities such as running, walking, climbing, or dancing.
- Spontaneous bodily sensations – The “body high” of 1P-LSD can be characterized as proportionally very intense in comparison to its accompanying visual and cognitive effects. It behaves as a euphoric, fast-moving, sharp, and location-specific tingling sensation.
- Physical euphoria – It should be noted that this effect is not as reliably induceable as it is with substances like stimulants or entactogens, and can just as easily manifest as extreme physical discomfort without any apparent reason.
- Tactile enhancement – Feelings of enhanced tactile sensations are consistently present at moderate levels throughout most 1P-LSD experiences. Buy 1P-LSD Blotters, Order Cheap 1P-LSD Discreetly
Based on its structural similarity to LSD, 1P-LSD likely acts as a partial agonist at the 5-HT2A receptor.
The psychedelic effects are thought to primarily come from its efficacy at the 5-HT2A receptors distributed throughout the brain.
1P-LSD also likely displays binding activity at a wide range of monoamine receptors, such as those for dopamine and norepinephrine.
However, there is currently no data to support these claims.
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Alcohol – Alcohol’s central depressant effects can be used to reduce some of the anxiety and tension produced by 1P-LSD.
However, alcohol can cause dehydration, nausea, and physical fatigue which can negatively impact the direction of the trip.
Benzodiazepines – Benzodiazepines are highly effective at reducing the intensity of 1P-LSD’s effects through the general suppression of brain activity.
Cannabis – Cannabis strongly intensifies the sensory and cognitive effects of 1P-LSD.
Extreme caution is advised when using this combination as it can significantly increase the chances of a negative psychological reaction like anxiety, confusion, and psychosis.
Psychedelics – When used in combination with other psychedelics, 1P-LSD’s physical, cognitive, visual, auditory, and transpersonal effects intensify and synergize strongly.
Stimulants – Combined with psychedelics, stimulants can cause severe Anxiety, Panic attacks, Thought loops, and Paranoia. Buy 1P-LSD Blotters, Order Cheap 1P-LSD Discreetly.
MDMA – 1P-LSD and MDMA are highly synergistic and mutually enhance each other’s physical, cognitive, and visual effects.
The synergy between these substances is unpredictable, and it is advised to start with markedly lower doses than one would take for each individual.
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