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Bk-Ethyl-K Crystals is a novel stimulant-entactogen substance of the cathinone class. Buy BK-Ethyl-K Crystals, Order Cheap Ephylone Crystal 50g.
Ephylone is chemically related to pentylone and belongs to a group of compounds known as the substituted cathinone.
Little is known about its pharmacology, although it likely produces its effects by increasing levels of serotonin, dopamine, and norepinephrine in the brain.
Ephylone was developed in the 1960s by Boehringer Ingelheim as a central nervous system stimulant, although it never became marketed. Reports of recreational use first appeared in late 2015.
Since then, its prevalence has steadily risen, particularly at dance music festivals where it appears as an adulterant or counterfeit for MDMA. Ephylone has been linked to numerous hospitalizations and overdose deaths.
User reports indicate that ephylone produces a mixture of classic stimulant and entactogenic effects resembling those of MDMA, methylone, and cocaine.
Typical effects include stimulation, disinhibition, increased libido, compulsive redosing, and euphoria. Unlike similar substances, however, ephylone is reported to be very long-lasting when taken in larger doses.
The significance of this is not known, although it may indicate that it has a different toxicity profile compared to other stimulants.
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Compared to other stimulant-entactogens, ephylone is reported to be more stimulating than entactogenic.
Entactogenic feelings are said to be weak compared to substances like MDMA, 6-APB, or methylone. Ephylone is also described as less euphoric and satisfying than traditional entactogens.
Reports suggest that the physical side effects increase disproportionately to the desirable effects, which may promote compulsive redosing. Buy BK-Ethyl-K Crystals, Order Cheap Ephylone Crystal 50g
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The effects which occur during the offset of a stimulant experience generally feel negative and uncomfortable in comparison to the effects which occurred during its peak.
This is often referred to as a “comedown” or “crash” and occurs because of neurotransmitter depletion. Its effects commonly include:
- Cognitive fatigue
- Motivation suppression
- Thought deceleration
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Very little data exists on the human pharmacokinetics and pharmacodynamics of ethylone and other substituted cathinones. Buy BK-Ethyl-K Crystals, Order Cheap Ephylone Crystal 50g.
Like amphetamines, synthetic cathinones exert their stimulating and sympathomimetic effects via increasing synaptic concentration of catecholamines such as dopamine, serotonin, and norepinephrine.
These molecules are able to inhibit monoamine reuptake transporters producing a decreased clearance of the neurotransmitters from the synapse.
Furthermore, they may cause a release of biogenic amines from intracellular stores.
Synthetic cathinones are generally less able than amphetamines to cross the blood–brain barrier because the beta-keto group causes an increase in polarity. Buy BK-Ethyl-K Crystals, Order Cheap Ephylone Crystal 50g.
Unlike other synthetic cathinones, pyrrolidine derivatives have a higher ability to cross the blood–brain barrier because the pyrrolidine ring confers a low polarity to these molecules.
The studies on the metabolism of synthetic cathinones have shown that they are N-demethylated, the keto group is reduced to hydroxyl, and ring alkyl groups are oxidized. Buy BK-Ethyl-K Crystals, Order Cheap Ephylone Crystal 50g.
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As with other stimulants, the chronic use of ephylone can be considered moderately addictive with a high potential for abuse. It is capable of causing psychological dependence among certain users.
When addiction has developed, cravings and withdrawal effects will occur if one suddenly stops their use.
Tolerance to many of the effects of ephylone develops with prolonged and repeated use. This results in users having to administer increasingly large doses to achieve the same effects.